Makoto Kodama Selected Research

Myocarditis (Carditis)

4/2013	Estimation of paracrine signaling using quantitative RT-PCR from multiple patchy lesion samples.
10/2012	Involvement of AMPK and MAPK signaling during the progression of experimental autoimmune myocarditis in rats and its blockade using a novel antioxidant.
9/2012	Systemic transplantation of allogenic fetal membrane-derived mesenchymal stem cells suppresses Th1 and Th17 T cell responses in experimental autoimmune myocarditis.
4/2012	Olmesartan attenuates the development of heart failure after experimental autoimmune myocarditis in rats through the modulation of ANG 1-7 mas receptor.
3/2012	Modulation of endoplasmic reticulum stress and cardiomyocyte apoptosis by mulberry leaf diet in experimental autoimmune myocarditis rats.
2/2012	Telmisartan acts through the modulation of ACE-2/ANG 1-7/mas receptor in rats with dilated cardiomyopathy induced by experimental autoimmune myocarditis.
2/2012	Quercetin offers cardioprotection against progression of experimental autoimmune myocarditis by suppression of oxidative and endoplasmic reticulum stress via endothelin-1/MAPK signalling.
10/2011	Inhibition of cardiac oxidative and endoplasmic reticulum stress-mediated apoptosis by curcumin treatment contributes to protection against acute myocarditis.
3/2011	Sulfated polysaccharide fucoidan ameliorates experimental autoimmune myocarditis in rats.
2/2011	Olmesartan, an AT1 antagonist, attenuates oxidative stress, endoplasmic reticulum stress and cardiac inflammatory mediators in rats with heart failure induced by experimental autoimmune myocarditis.

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Makoto Kodama Research Topics

Disease

57	Myocarditis (Carditis) 04/2013 - 01/2002
36	Fibrosis (Cirrhosis) 01/2019 - 04/2002
33	Heart Failure 04/2012 - 04/2002
25	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 05/2016 - 01/2002
17	Inflammation (Inflammations) 11/2020 - 01/2002
17	Body Weight (Weight, Body) 05/2013 - 01/2002
15	Hypertrophy 07/2012 - 01/2003
8	Left Ventricular Dysfunction 07/2010 - 09/2004
7	Cardiomegaly (Heart Hypertrophy) 01/2011 - 02/2005
6	Cardiotoxicity 01/2012 - 06/2006
5	Infections 03/2017 - 12/2004
5	Coronary Artery Disease (Coronary Atherosclerosis) 09/2010 - 10/2006
5	Ischemia 10/2008 - 02/2004
4	Neoplasms (Cancer) 07/2021 - 06/2006
4	Myocardial Infarction 08/2010 - 07/2003
4	Ventricular Remodeling 09/2009 - 02/2005
3	Hyperglycemia 12/2018 - 05/2008
3	Diabetic Nephropathies (Diabetic Nephropathy) 01/2012 - 05/2011
3	Atrial Fibrillation 05/2011 - 01/2011
3	Heart Diseases (Heart Disease) 01/2011 - 01/2002
3	Diabetic Cardiomyopathies 05/2008 - 06/2005
2	Diabetes Mellitus 12/2018 - 09/2009
2	Virus Diseases (Viral Diseases) 09/2014 - 05/2013
2	Human Influenza (Influenza) 05/2013 - 11/2011
2	Cardiovascular Diseases (Cardiovascular Disease) 07/2012 - 02/2012
2	Kidney Diseases (Kidney Disease) 01/2012 - 01/2011
2	Fever (Fevers) 11/2010 - 11/2005
2	Renal Insufficiency (Renal Failure) 03/2010 - 12/2007
2	Liver Failure 09/2009 - 01/2003
2	Atherosclerotic Plaque (Atheroma) 05/2009 - 10/2006

Drug/Important Bio-Agent (IBA)

18	CytokinesIBA 05/2013 - 01/2002
14	Atrial Natriuretic Factor (ANF)IBA 07/2012 - 01/2003
13	CollagenIBA 02/2012 - 09/2003
12	Cardiac MyosinsIBA 07/2012 - 04/2002
11	Proteins (Proteins, Gene)FDA Link 07/2021 - 04/2006
11	Messenger RNA (mRNA)IBA 01/2013 - 01/2003
8	AngiotensinsIBA 10/2012 - 12/2003
8	Myosins (Myosin)IBA 07/2012 - 01/2007
8	Transforming Growth Factor beta1 (TGF beta 1)IBA 11/2010 - 04/2002
6	olmesartanIBA 07/2012 - 11/2010
6	Telmisartan (Micardis)FDA Link 02/2012 - 07/2010
6	InterleukinsIBA 06/2011 - 12/2004
6	Angiotensin IIIBA 01/2011 - 02/2004
6	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 07/2004 - 01/2003
5	peramivirIBA 03/2017 - 11/2011
5	AntioxidantsIBA 10/2012 - 04/2006
5	Angiotensin Receptor AntagonistsIBA 01/2011 - 01/2003
4	Interleukin-1 (Interleukin 1)IBA 04/2013 - 04/2005
4	DiureticsIBA 10/2012 - 06/2006
4	EdaravoneIBA 09/2012 - 04/2006
4	Streptozocin (Streptozotocin)FDA Link 01/2012 - 06/2005
4	Angiotensin II Type 1 Receptor BlockersIBA 02/2011 - 01/2003
4	Daunorubicin (Cerubidine)FDA LinkGeneric 12/2010 - 06/2006
4	Carvedilol (Coreg)FDA LinkGeneric 07/2010 - 04/2002
4	Sodium Potassium Chloride Symporter Inhibitors (Loop Diuretics)IBA 07/2009 - 02/2008
4	14-3-3 Proteins (14-3-3 Protein)IBA 05/2008 - 06/2005
4	Brain Natriuretic Peptide (Natrecor)FDA Link 01/2008 - 01/2003
3	Antiviral Agents (Antivirals)IBA 03/2017 - 01/2005
3	Calcium Channel Blockers (Blockers, Calcium Channel)IBA 10/2012 - 09/2004
3	Peptides (Polypeptides)IBA 04/2012 - 10/2007
3	angiotensin I (1-7)IBA 02/2012 - 01/2011
3	Fibronectins (Fibronectin)IBA 01/2012 - 09/2003
3	Interleukin-6 (Interleukin 6)IBA 11/2011 - 10/2006
3	Glutathione PeroxidaseIBA 12/2010 - 04/2006
3	AnthracyclinesIBA 11/2010 - 06/2006
3	C-Reactive ProteinIBA 09/2010 - 10/2006
3	Biomarkers (Surrogate Marker)IBA 03/2010 - 09/2008
3	p38 Mitogen-Activated Protein KinasesIBA 09/2009 - 04/2006
3	Cytochrome P-450 CYP11B2 (CYP11B2)IBA 07/2009 - 02/2008
3	Furosemide (Lasix)FDA LinkGeneric 07/2009 - 02/2008
3	Torsemide (Demadex)FDA LinkGeneric 07/2009 - 02/2008
3	DNA (Deoxyribonucleic Acid)IBA 09/2008 - 04/2005
3	Interleukin-10 (Interleukin 10)IBA 01/2005 - 01/2002
3	Quinapril (Accupril)FDA LinkGeneric 07/2004 - 01/2003
2	Oseltamivir (Tamiflu)FDA Link 05/2013 - 11/2011
2	4- ethoxymethylene- 2- phenyl- 2- oxazoline- 5- one (phOx)IBA 09/2012 - 03/2012
2	HepcidinsIBA 06/2012 - 08/2010
2	Angiotensin-Converting Enzyme 2IBA 04/2012 - 01/2011
2	Superoxides (Superoxide)IBA 03/2012 - 05/2011
2	PowdersIBA 03/2012 - 10/2007
2	candesartan cilexetil (Amias)FDA Link 01/2012 - 01/2005
2	CurcuminIBA 10/2011 - 01/2011
2	Pharmaceutical PreparationsIBA 06/2011 - 01/2011
2	Antihypertensive Agents (Antihypertensives)IBA 05/2011 - 01/2011
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2011 - 01/2011
2	Natriuretic PeptidesIBA 01/2011 - 01/2003
2	Malondialdehyde (Propanedial)IBA 12/2010 - 11/2010
2	Free RadicalsIBA 11/2010 - 08/2010
2	Angiotensin Receptors (Angiotensin II Receptor)IBA 11/2010 - 01/2003
2	IronIBA 08/2010 - 03/2010
2	Losartan (Cozaar)FDA LinkGeneric 08/2009 - 04/2006
2	AldosteroneIBA 07/2009 - 02/2005
2	Therapeutic UsesIBA 07/2009 - 02/2008
2	oxidized low density lipoproteinIBA 05/2009 - 05/2008

Therapy/Procedure

12	Therapeutics 12/2018 - 07/2003
4	Transplantation 11/2020 - 01/2003
4	Oral Administration 01/2005 - 04/2002
2	Nephrectomy 01/2019 - 09/2005
2	Intravenous Injections 05/2013 - 11/2011
2	Percutaneous Coronary Intervention 05/2009 - 10/2006